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Bioss
IL-1 Alpha Propeptide Polyclonal Antibody
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Product Details
BS-10540R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human IL-1 Alpha Propeptide, amino acids 21-113.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.03% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Hematopoietin-1; IL-1 alpha; Interleukin; interleukin 1, alpha; Interleukin-1 alpha; preinterleukin 1 alpha; pro-interleukin-1-alpha
Gene Aliases: IL-1 alpha; IL-1A; IL1; IL1-ALPHA; IL1A; IL1F1
UniProt ID: (Human) P01583, (Mouse) P01582, (Rat) P16598
Entrez Gene ID: (Human) 3552, (Mouse) 16175, (Rat) 24493
fever generation
connective tissue replacement involved in inflammatory response wound healing
apoptotic process
inflammatory response
immune response
cell proliferation
negative regulation of cell proliferation
positive regulation of vascular endothelial growth factor production
positive regulation of gene expression
cytokine-mediated signaling pathway
cellular response to heat
ectopic germ cell programmed cell death
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of interleukin-2 biosynthetic process
positive regulation of angiogenesis
positive regulation of mitotic nuclear division
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JNK cascade
response to copper ion
positive regulation of protein secretion
positive regulation of cytokine secretion
positive regulation of cell division
extrinsic apoptotic signaling pathway in absence of ligand
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
positive regulation of steroid biosynthetic process
keratinization
positive regulation of prostaglandin secretion
positive regulation of interleukin-6 production
positive regulation of stress-activated MAPK cascade
regulation of sensory perception of pain
positive regulation of ERK1 and ERK2 cascade
positive regulation of neutrophil migration
response to hypoxia
acute inflammatory response
spermatogenesis
heart development
response to heat
response to organic substance
response to ozone
response to organonitrogen compound
response to gamma radiation
response to organic cyclic compound
response to lipopolysaccharide
response to L-ascorbic acid
wound healing
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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