Product References
A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma.
Nature immunology
Harb H,Stephen-Victor E,Crestani E,Benamar M,Massoud A,Cui Y,Charbonnier LM,Arbag S,Baris S,Cunnigham A,Leyva-Castillo JM,Geha RS,Mousavi AJ,Guennewig B,Schmitz-Abe K,Sioutas C,Phipatanakul W,Chatila TA
500-P54 was used in Flow cytometry/Cell sorting to find that interleukin-6- and STAT3 transcription factor-dependent upregulation of Notch4 receptor on lung tissue regulatory T (Treg) cells is necessary for allergens and particulate matter pollutants to promote airway inflammation.
Sun Nov 01 00:00:00 EDT 2020
A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma.
Nature immunology
Harb H,Stephen-Victor E,Crestani E,Benamar M,Massoud A,Cui Y,Charbonnier LM,Arbag S,Baris S,Cunnigham A,Leyva-Castillo JM,Geha RS,Mousavi AJ,Guennewig B,Schmitz-Abe K,Sioutas C,Phipatanakul W,Chatila TA
500-P54 was used in Flow cytometry/Cell sorting to find that interleukin-6- and STAT3 transcription factor-dependent upregulation of Notch4 receptor on lung tissue regulatory T (Treg) cells is necessary for allergens and particulate matter pollutants to promote airway inflammation.
Sun Nov 01 00:00:00 EDT 2020
Calcitriol Regulates the Differentiation of IL-9-Secreting Th9 Cells by Modulating the Transcription Factor PU.1.
Journal of immunology (Baltimore, Md. : 1950)
Vyas SP,Hansda AK,Kaplan MH,Goswami R
Sun Mar 01 00:00:00 EST 2020
GAPDH Overexpression in the T Cell Lineage Promotes Angioimmunoblastic T Cell Lymphoma through an NF-κB-Dependent Mechanism.
Cancer cell
Mondragón L,Mhaidly R,De Donatis GM,Tosolini M,Dao P,Martin AR,Pons C,Chiche J,Jacquin M,Imbert V,Proïcs E,Boyer L,Doye A,Luciano F,Neels JG,Coutant F,Fabien N,Sormani L,Rubio-Patiño C,Bossowski JP,Muller F,Marchetti S,Villa E,Peyron JF,Gaulard P,Lemonnier F,Asnafi V,Genestier L,Benhida R,Fournié JJ,Passeron T,Ricci JE,Verhoeyen E
Mon Sep 16 00:00:00 EDT 2019
RHOA G17V Induces T Follicular Helper Cell Specification and Promotes Lymphomagenesis.
Cancer cell
Cortes JR,Ambesi-Impiombato A,Couronné L,Quinn SA,Kim CS,da Silva Almeida AC,West Z,Belver L,Martin MS,Scourzic L,Bhagat G,Bernard OA,Ferrando AA,Palomero T
Mon Feb 12 00:00:00 EST 2018
Silibinin alleviates inflammation and induces apoptosis in human rheumatoid arthritis fibroblast-like synoviocytes and has a therapeutic effect on arthritis in rats.
Scientific reports
Tong WW,Zhang C,Hong T,Liu DH,Wang C,Li J,He XK,Xu WD
Mon Feb 19 00:00:00 EST 2018
Constitutive expression of NF-κB inducing kinase in regulatory T cells impairs suppressive function and promotes instability and pro-inflammatory cytokine production.
Scientific reports
Polesso F,Sarker M,Anderson A,Parker DC,Murray SE
Tue Nov 07 00:00:00 EST 2017
Transcriptomics identified a critical role for Th2 cell-intrinsic miR-155 in mediating allergy and antihelminth immunity.
Proceedings of the National Academy of Sciences of the United States of America
Okoye IS,Czieso S,Ktistaki E,Roderick K,Coomes SM,Pelly VS,Kannan Y,Perez-Lloret J,Zhao JL,Baltimore D,Langhorne J,Wilson MS
Tue Jul 29 00:00:00 EDT 2014
GM-CSF contributes to aortic aneurysms resulting from SMAD3 deficiency.
The Journal of clinical investigation
Ye P,Chen W,Wu J,Huang X,Li J,Wang S,Liu Z,Wang G,Yang X,Zhang P,Lv Q,Xia J
Wed May 01 00:00:00 EDT 2013
SAHA, an HDAC inhibitor, synergizes with tacrolimus to prevent murine cardiac allograft rejection.
Cellular & molecular immunology
Zhang X,Han S,Kang Y,Guo M,Hong S,Liu F,Fu S,Wang L,Wang QX
Sat Sep 01 00:00:00 EDT 2012
Th2-associated alternative Kupffer cell activation promotes liver fibrosis without inducing local inflammation.
International journal of biological sciences
López-Navarrete G,Ramos-Martínez E,Suárez-Álvarez K,Aguirre-García J,Ledezma-Soto Y,León-Cabrera S,Gudiño-Zayas M,Guzmán C,Gutiérrez-Reyes G,Hernández-Ruíz J,Camacho-Arroyo I,Robles-Díaz G,Kershenobich D,Terrazas LI,Escobedo G
Tue May 29 00:00:00 EDT 2012
Impact of a probiotic fermented milk in the gut ecosystem and in the systemic immunity using a non-severe protein-energy-malnutrition model in mice.
BMC gastroenterology
Maldonado Galdeano C,Novotny Núñez I,de Moreno de LeBlanc A,Carmuega E,Weill R,Perdigón G
Thu May 26 00:00:00 EDT 2011
Control of T helper cell differentiation through cytokine receptor inclusion in the immunological synapse.
The Journal of experimental medicine
Maldonado RA,Soriano MA,Perdomo LC,Sigrist K,Irvine DJ,Decker T,Glimcher LH
Mon Apr 13 00:00:00 EDT 2009
Cutting edge: Ikaros is a regulator of Th2 cell differentiation.
Journal of immunology (Baltimore, Md. : 1950)
Quirion MR,Gregory GD,Umetsu SE,Winandy S,Brown MA
Thu Jan 15 00:00:00 EST 2009
The TNF-family receptor DR3 is essential for diverse T cell-mediated inflammatory diseases.
Immunity
Meylan F,Davidson TS,Kahle E,Kinder M,Acharya K,Jankovic D,Bundoc V,Hodges M,Shevach EM,Keane-Myers A,Wang EC,Siegel RM
Fri Jul 18 00:00:00 EDT 2008
The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease.
The Journal of experimental medicine
Chong MM,Rasmussen JP,Rudensky AY,Littman DR
Mon Sep 01 00:00:00 EDT 2008
Loss of STAT3 in CD4+ T cells prevents development of experimental autoimmune diseases.
Journal of immunology (Baltimore, Md. : 1950)
Liu X,Lee YS,Yu CR,Egwuagu CE
Thu May 01 00:00:00 EDT 2008
SOCS1 regulates CCR7 expression and migration of CD4+ T cells into peripheral tissues.
Journal of immunology (Baltimore, Md. : 1950)
Yu CR,Mahdi RM,Liu X,Zhang A,Naka T,Kishimoto T,Egwuagu CE
Tue Jul 15 00:00:00 EDT 2008
Immunomodulatory effects of aqueous birch pollen extracts and phytoprostanes on primary immune responses in vivo.
The Journal of allergy and clinical immunology
Gutermuth J,Bewersdorff M,Traidl-Hoffmann C,Ring J,Mueller MJ,Behrendt H,Jakob T
Wed Aug 01 00:00:00 EDT 2007
Notch signaling is an important regulator of type 2 immunity.
The Journal of experimental medicine
Tu L,Fang TC,Artis D,Shestova O,Pross SE,Maillard I,Pear WS
Mon Oct 17 00:00:00 EDT 2005
Effects of milk fermented by Lactobacillus helveticus R389 on a murine breast cancer model.
Breast cancer research : BCR
de Moreno de LeBlanc A,Matar C,LeBlanc N,Perdigón G
500-P54 was used in Immunohistochemistry to conclude that the milk fermented by L. helveticus R389 was able to modulate the relationship between immune and endocrine systems (by IL-6 diminution), which is very important in oestrogen-dependent tumour and induced cellular apoptosis.
Wed Jan 25 00:00:00 EST 2006
Effects of milk fermented by Lactobacillus helveticus R389 on a murine breast cancer model.
Breast cancer research : BCR
de Moreno de LeBlanc A,Matar C,LeBlanc N,Perdigón G
500-P54 was used in Immunohistochemistry to conclude that the milk fermented by L. helveticus R389 was able to modulate the relationship between immune and endocrine systems (by IL-6 diminution), which is very important in oestrogen-dependent tumour and induced cellular apoptosis.
Wed Jan 25 00:00:00 EST 2006
Cell proliferation and STAT6 pathways are negatively regulated in T cells by STAT1 and suppressors of cytokine signaling.
Journal of immunology (Baltimore, Md. : 1950)
Yu CR,Mahdi RM,Ebong S,Vistica BP,Chen J,Guo Y,Gery I,Egwuagu CE
Thu Jul 15 00:00:00 EDT 2004