|Tested species reactivity||Pig|
|Published species reactivity||Pig, Not Applicable|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant porcine IL-6|
|Tested Applications||Dilution *|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PP690 targets IL-6 in WB applications and shows reactivity with Porcine samples.
The PP690 immunogen is recombinant porcine IL-6.
PP690 detects IL-6 which has a predicted molecular weight of approximately 21 kDa.
This product is a Low Endotoxin formulation.
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Development and application of specific cytokine assays in tissue samples from a bottlenose dolphin with hyperinsulinemia.
PP690 was used in immunohistochemistry - frozen section to characterize a dolphin with insulin resistance and fatty liver disease
|Eberle KC,Waters TE,Jensen ED,Venn-Watson SK,Sacco RE||Frontiers in endocrinology (4:null)||2013|
Development of a novel antigen capture-ELISA using IgY against porcine interleukin-6 and its application.
PP690 was used in western blot to develop a novel antigen capture-ELISA for measuring porcine IL-6 using IgY
|Lee DY,Cho YW,Kang SG,Shin SJ,Yoo HS||Journal of veterinary science (5:337)||2004|