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|Tested species reactivity||Mouse|
|Published species reactivity||Mouse|
|Host / Isotype||Rat / IgG1, kappa|
|Immunogen||Recombinant mouse IL-6.|
|Contains||0.1% sodium azide|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Flow Cytometry (Flow)||Assay Dependent|
|Immunohistochemistry (IHC)||Assay Dependent|
|Neutralization (Neu)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Interleukin 6 is a cytokine secreted by T cells and macrophages, has shown to exhibit activity in response to tissue damage and infection. They have also been found to be involved in various other activities like development of blood, cancer, embryonic development, and regulation of the immune system. IL6 is included in a family of other cytokines which include ciliary neurotrophic factor, cardiotrophin-1, leukemia inhibitory factor and interleukin 11. IL-6 can bring about differentiation through a receptor system which requires a specific receptor and a signaling subunit, gp130.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Exosome derived from epigallocatechin gallate treated breast cancer cells suppresses tumor growth by inhibiting tumor-associated macrophage infiltration and M2 polarization.
||Jang JY,Lee JK,Jeon YK,Kim CW||BMC cancer (13:null)||2013|
Toll-like receptor 4 contributes to retinal ischemia/reperfusion injury.
||Dvoriantchikova G,Barakat DJ,Hernandez E,Shestopalov VI,Ivanov D||Molecular vision (16:1907)||2010|
B-cell hybridoma growth factor, interleukin HP-1, interleukin-6, BSF2, HGF, HSF, IFNB2