In direct ELISAs, approximately 30% cross-reactivity with recombinant mouse IL-9 is observed, and approximately 10% cross-reactivity with recombinant human IL-9 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
Interleukin 9 (IL9) is a cytokine that regulates a variety of hematopoietic cells. It is secreted by T-cells, and supports IL-2 independent, and IL-4 independent growth of helper T-cells. It is also a positive regulator of cell proliferation, and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates signal transducer and activator (STAT) proteins and results in IRS1 and IRS2/PI3K and MEK/ERK signaling cascades.
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