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Fabgennix
IL18RAP Polyclonal Antibody
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Product Details
IL18RAP-101AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken within amino acid region 500-550 on human Interleukin-18 receptor accessory protein.
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-kappaB and MAPK8 (JNK) in response to IL18.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Accessory protein-like; AcPL; AcPL accessory protein-like); CD218 antigen-like family member B; CD218b; CDw218b; cluster of differentiation w218b; IL-18 RA; IL-18 receptor accessory protein; IL-18 receptor beta; IL-18R-beta; IL-18Rbeta splice variant; interleukin 18 receptor accessory protein splice variant; IL-1R accessory protein-like; IL-1R-7; IL-1RAcPL; Interleukin-1 receptor 7; Interleukin-18 receptor accessory protein; Interleukin-18 receptor accessory protein-like; Interleukin-18 receptor beta; unnamed protein product
Gene Aliases: ACPL; CD218b; CDw218b; IL-18R-beta; IL-18RAcP; IL-18Rbeta; IL-1R-7; IL-1R7; IL-1RAcPL; IL18RAP; IL18RB; IL1R7
UniProt ID: (Human) O95256, (Mouse) Q9Z2B1
Entrez Gene ID: (Human) 8807, (Rat) 373540, (Mouse) 16174
adaptive immune response
immune system process
inflammatory response
immune response
signal transduction
cell proliferation
interleukin-18-mediated signaling pathway
neutrophil activation
positive regulation of natural killer cell mediated cytotoxicity
positive regulation of NF-kappaB transcription factor activity
cellular response to hydrogen peroxide
cellular response to cytokine stimulus
cellular response to interleukin-18
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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