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Invitrogen
IL1F10 Polyclonal Antibody
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FIGURE: 1 / 2
IL1F10 Antibody (PA5-79486) in IHC (P)
Immunohistochemistry analysis of IL1F10 on paraffin-embedded human tonsil tissue. Antigen retrieval was performed using citrate buffer (pH6, epitope retrieval solution) for 20 mins. Sample was blocked using 10% goat serum, incubated with IL1F10 polyclonal antibody (Product# PA5-79486) with a dilution of 1 µg/mL (overnight at 4°C), and followed by biotinylated goat anti-rabbit IgG (30 minutes at 37°C). Devel... View More
Product Details
PA5-79486
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived human IL1F10 recombinant protein (Position: M1-W152).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human U87MG whole cell, human placenta tissue. IHC: human tonsil tissue.
Target Information
The cytokine IL-1 is responsible for initiating a variety of activities through the activation of transcription factors, NF-kappa B and AP-1, thereby promoting host response to injury or infection. IL-1F10 (Interleukin-1 family member 10), also known as FIL1T, IL1HY2 or FKSG75, is highly expressed in the skin, spleen and proliferating B-cells of the tonsil. IL-1F10 binds soluble IL-1 receptor type 1, and is one of nine Interleukin 1 families clustered on chromosome 2, where it is thought to participate in the regulation of adapted and innate immune responses. IL-1F10 and IL-1RN polymorphisms may play an important role in the susceptibility to developing rheumatoid arthritis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Family of interleukin 1-theta; FIL1 theta; IL-1 theta; IL-1F10; IL-1F10 (canonical form IL-1F10a); IL-1HY2; IL-38; Interleukin; interleukin 1 family member 10 (theta); Interleukin-1 family member 10; Interleukin-1 HY2; interleukin-1 receptor antagonist FKSG75; interleukin-1 receptor antagonist-like FIL1 theta; Interleukin-1 theta; Interleukin-38
Gene Aliases: FIL1-theta; FIL1T; FKSG75; IL-1HY2; IL-38; IL1-theta; IL1F10; IL1HY2; IL38; UNQ6119/PRO20041
UniProt ID: (Human) Q8WWZ1
Entrez Gene ID: (Human) 84639
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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