In direct ELISAs, approximately 25% cross-reactivity with recombinant human (rh) IL-1 R6 is observed and less than 5% cross-reactivity with rhIL-18 R beta, rhIL-1 RI, and rhIL-1 RII is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.
The protein encoded by this gene is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. This gene and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.
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Protein Aliases: IL-1Rrp2; IL-36 receptor; IL1R-rp2; Interleukin-1 receptor-like 2; Interleukin-1 receptor-related protein 2
Gene Aliases: Il1rl2
UniProt ID: (Rat) Q62929
Entrez Gene ID: (Rat) 171106