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Invitrogen
IL36B Polyclonal Antibody
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FIGURE: 1 / 3
IL36B Antibody (PA5-81415) in IHC (P)
Immunohistochemical staining of mouse IL36B in mouse intestine with IL36B Polyclonal Antibody (Product # PA5-81415, 1:1,000, formalin-fixed paraffin embedded sections). Left panel: tissue incubated with primary antibody; Right panel: tissue incubated with mixture of primary antibody and antigen (recombinant protein).
Product Details
PA5-81415
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Mouse IL-36B/IL-1F8 protein (Met1-Lys183)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Mouse IL-36B/IL-1F8.
Target Information
IL-36B is is a member of the interleukin 1 cytokine family whose gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. IL-36B is thought to activate the NF-kappaB pathway through IL-1 receptor family members IL-1RL2 and IL-1RAcP. Like the related proteins IL-36A and IL-36G, IL-36B requires post-translational processing for full agonist activity, but the cleavage mechanism is currently unknown. The IL-36 cytokines have been suggested to amplify Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: IL-1F8; Interleukin; Interleukin-1 family member 8; Interleukin-36 beta
Gene Aliases: 2310043N20Rik; Fil1e; Il1f8; Il36b
UniProt ID: (Mouse) Q9D6Z6
Entrez Gene ID: (Mouse) 69677
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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