Immunogen sequence: PLLFDDLPPA SSTDSGSGGP LLFDDLPPAS SGDSGSLATS ISQMVKTEGK GAKRKTSEEE KNGSEELVEK KVCKASSVIF GLKGYVAERK GEREEMQDAH V
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 88%.
The protein encoded by this gene is a protein serine/threonine phosphatase of the PP2C family. This protein can interact with integrin-linked kinase (ILK/ILK1), a regulator of integrin mediated signaling, and regulate the kinase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: delta isozyme; ILKAP; ILKAP2; ILKAP3; integrin-linked kinase associated phosphatase; Integrin-linked kinase-associated serine/threonine phosphatase 2C; PP2C-DELTA; protein phosphatase 2c; protein phosphatase 2c, delta isozyme; protein phosphatase, Mg2+/Mn2+ dependent 1O
Gene Aliases: 0710007A14Rik; 1600009O09Rik; ILKAP; ILKAP2; ILKAP3; PP2C-DELTA; PPM1O