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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide: E(71) E K G H E Y I N N I H L T(84)|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-4276 detects the ILP-2 protein in human samples.
PA1-4276 has been successfully used in Western blot procedures.
PA1-4276 immunogen corresponds to amino acid residues 71-84 of the human ILP-2 protein.
Inhibitor of apoptosis protein (IAP)-like protein-1 (ILP-1) is a potent inhibitor of apoptosis and exerts its effects, at least in part, by the direct association with and inhibition of specific caspases. ILP-2 is a novel human gene that is related to ILP-1, and in normal tissues is expressed solely in testis. ILP-2 potently inhibited apoptosis induced by overexpression of Bax or by coexpression of caspase 9 with Apaf-1, suggesting that ILP-2 is a has restricted specificity for caspase 9.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
baculoviral IAP repeat-containing 8; IAP-like protein 2; ILP-2; inhibitor of apoptosis-like protein 2; testis-specific inhibitor of apoptosis
BIRC8; hILP2; ILP-2; ILP2