PA1-4276 detects the ILP-2 protein in human samples.
PA1-4276 has been successfully used in Western blot procedures.
PA1-4276 immunogen corresponds to amino acid residues 71-84 of the human ILP-2 protein.
Inhibitor of apoptosis protein (IAP)-like protein-1 (ILP-1) is a potent inhibitor of apoptosis and exerts its effects, at least in part, by the direct association with and inhibition of specific caspases. ILP-2 is a novel human gene that is related to ILP-1, and in normal tissues is expressed solely in testis. ILP-2 potently inhibited apoptosis induced by overexpression of Bax or by coexpression of caspase 9 with Apaf-1, suggesting that ILP-2 is a has restricted specificity for caspase 9.
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Protein Aliases: baculoviral IAP repeat-containing 8; Baculoviral IAP repeat-containing protein 8; IAP-like protein 2; ILP-2; Inhibitor of apoptosis-like protein 2; Testis-specific inhibitor of apoptosis
Gene Aliases: BIRC8; hILP2; ILP-2; ILP2
UniProt ID: (Human) Q96P09
Entrez Gene ID: (Human) 112401