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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • IMPDH1 Antibodies

          Invitrogen

          IMPDH1 Polyclonal Antibody

          1 Published Figure
          1 Reference
          View all (8) IMPDH1 antibodies

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          Cite IMPDH1 Polyclonal Antibody

          • Antibody Testing Data (1)
          • Published Figures (1)
          IMPDH1 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          IMPDH1 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          IMPDH1 Antibody (PA5-27792) in WB

          Western Blot using IMPDH1 Polyclonal Antibody (Product # PA5-27792). Sample (30 µg of whole cell lysate). Lane A: Raji . 7.5% SDS PAGE. IMPDH1 Polyclonal Antibody (Product # PA5-27792) diluted at 1:1,000. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          IMPDH1 Antibody in Western Blot (WB)
          IMPDH1 Antibody in Immunoprecipitation (IP)

          Product Details

          PA5-27792

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:3,000
          -

          Immunoprecipitation (IP)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein encompassing a sequence within the center region of human IMPDH1. The exact sequence is proprietary.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          0.1M tris glycine, pH 7, with 10% glycerol

          Contains

          0.01% thimerosal

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2545268

          Product Specific Information

          Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji.

          Predicted reactivity: Mouse (95%), Rat (82%), Xenopus laevis (88%), Bovine (97%).

          Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

          Target Information

          The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.

          ⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: DKFZp781N0678; IMP (inosine 5'-monophosphate) dehydrogenase 1; IMP (inosine monophosphate) dehydrogenase 1; IMP dehydrogenase 1; IMPD 1; IMPDH 1; IMPDH-I; Inosine-5'-monophosphate dehydrogenase 1

          View more View less

          Gene Aliases: IMPD; IMPD1; IMPDH-I; IMPDH1; LCA11; RP10; sWSS2608

          View more View less

          UniProt ID: (Human) P20839

          View more View less

          Entrez Gene ID: (Human) 3614

          View more View less

          Function(s)
          nucleotide binding nucleic acid binding DNA binding RNA binding IMP dehydrogenase activity metal ion binding dehydrogenase
          Process(es)
          GMP biosynthetic process purine ribonucleoside monophosphate biosynthetic process response to cold lymphocyte proliferation oxidation-reduction process retina development in camera-type eye
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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