Proteintech

ING2 Polyclonal Antibody

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ING2 Antibody in Immunofluorescence (IF) — Immunofluorescent analysis of ( 10% Formaldehyde ) fixed HEK-293 cells using 11560-1-AP (ING2 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

ING2 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human cervical cancer using 11560-1-AP (ING2 antibody) at dilution of 1:50 (under 10x lens).

ING2 Antibody in Western Blot (WB) — Human liver tissue were subjected to SDS PAGE followed by western blot with 11560-1-AP (ING2 antibody) at dilution of 1:0 incubated at room temperature for 1.5 hours.

ING2 Antibody in Immunoprecipitation (IP) — IP result of anti-ING2 (IP:11560-1-AP, 3ug; Detection:11560-1-AP 1:500) with HEK-293 cells lysate 1000ug.

Product Details

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC)

1:50-1:500

Immunofluorescence (IF)

1:50-1:500

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunoprecipitation (IP)

0.5-4.0 µg

Western Blot (WB)

1:500-1:1000

View 5 publications 5 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Miscellaneous PubMed (Misc)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host / Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

ING2 Fusion Protein Ag2121

Conjugate

Unconjugated

Form

Liquid

Concentration

0.23 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.1% sodium azide

Storage conditions

-20°C

Product Specific Information

11560-1-AP is a rabbit polyclonal antibody raised against full length ING2 of human origin.

Target Information

This gene is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: ING1Lp; Inhibitor of growth 1-like protein; inhibitor of growth family, member 2; Inhibitor of growth protein 2; p32; p33ING2

Gene Aliases: 2810011M06Rik; ING1L; ING2; Ing2b; P33ING2

UniProt ID: (Human) Q9H160, (Mouse) Q9ESK4

Entrez Gene ID: (Human) 3622, (Mouse) 69260, (Rat) 290744

Molecular Function: DNA binding protein chromatin/chromatin-binding protein nucleic acid binding transcription cofactor transcription factor zinc finger transcription factor

Function(s)

transcription, DNA-templated regulation of transcription, DNA-templated male meiosis I signal transduction spermatogenesis spermatid development negative regulation of cell proliferation chromatin modification covalent chromatin modification sperm motility positive regulation of transforming growth factor beta receptor signaling pathway positive regulation of histone deacetylation regulation of growth positive regulation of apoptotic process positive regulation of transcription, DNA-templated male germ-line stem cell asymmetric division seminiferous tubule development negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator regulation of cellular senescence regulation of response to DNA damage stimulus negative regulation of apoptotic signaling pathway biological_process

Process(es)

DNA binding chromatin binding protein binding zinc ion binding protein complex binding methylated histone binding phosphatidylinositol binding metal ion binding molecular_function

ING2 Polyclonal Antibody

Product Details

Product Specific Information

Target Information

Bioinformatics

Material safety data sheets (MSDS)

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