ING5 is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway.
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Protein Aliases: inhibitor of growth family, member 5; Inhibitor of growth protein 5; p28ING5
Gene Aliases: 1700001C14Rik; 1700027H23Rik; 1810018M11Rik; AI225768; ING5; p28ING5