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Proteintech
ING5 Polyclonal Antibody
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Product Details
10665-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ING5 Fusion Protein Ag1059 (1-226 aa encoded by BC005370)
Conjugate
Form
Liquid
Concentration
0.21 mg/mL
Amount
31.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MATAMYLEH YLDSIENLPC ELQRNFQLMR ELDQRTEDKK AEIDILAAEY ISTVKTLSPD QRVERLQKIQ NAYSKCKEYS DDKVQLAMQT YEMVDKHIRR LDADLARFEA DLKDKMEGSD FESSGGRGLK KGRGQKEKRG SRGRGRRTSE EDTPKKKKHK GGSEFTDTIL SVHPSDVLDM PVDPNEPTYC LCHQVSYGEM IGCDNPDCPI EWFHFACVDL TTKPKGK (1-226 aa encoded by BC005370)
Target Information
ING5 is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Inhibitor of growth protein 5; p28ING5; unnamed protein product
Gene Aliases: 1700001C14Rik; 1700027H23Rik; 1810018M11Rik; AI225768; ING5; p28ING5
UniProt ID: (Human) Q8WYH8, (Mouse) Q9D8Y8
Entrez Gene ID: (Human) 84289, (Rat) 363292, (Mouse) 66262
regulation of cell growth
regulation of DNA replication
chromatin organization
regulation of transcription, DNA-templated
protein acetylation
negative regulation of cell proliferation
positive regulation of apoptotic process
negative regulation of growth
fibroblast proliferation
negative regulation of fibroblast proliferation
regulation of developmental process
regulation of cell cycle
apoptotic signaling pathway
DNA replication-dependent chromatin disassembly
regulation of hemopoiesis
regulation of DNA biosynthetic process
positive regulation of apoptotic signaling pathway
DNA replication
histone acetylation
histone H3 acetylation
positive regulation of transcription, DNA-templated
transcription, DNA-templated
chromatin modification
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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