Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
PA5-60081
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ING5. Recombinant protein control fragment (Product #RP-98925).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2642722
Product Specific Information
Immunogen sequence: EDKKAEIDIL AAEYISTVKT LSPDQRVERL QKIQNAYSKC KEYSDDKVQ
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.
Target Information
ING5 is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: inhibitor of growth family, member 5; Inhibitor of growth protein 5; p28ING5
Gene Aliases: ING5; p28ING5
UniProt ID: (Human) Q8WYH8
Entrez Gene ID: (Human) 84289
DNA replication
transcription, DNA-templated
protein acetylation
negative regulation of cell proliferation
chromatin modification
positive regulation of apoptotic process
histone H3 acetylation
positive regulation of transcription, DNA-templated
negative regulation of growth
regulation of signal transduction by p53 class mediator
positive regulation of apoptotic signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support