Invitrogen

INHA Polyclonal Antibody

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INHA Antibody in Immunofluorescence (IF) — Immunofluorescent analysis of INHA in U-2 OS cells using a INHA polyclonal antibody (Product # PA5-82667). The analysis shows localization to vesicles.

INHA Antibody in Immunohistochemistry (IHC) — Immunohistochemical analysis of INHA in human testis and endometrium tissues using a INHA polyclonal antibody (Product # PA5-82667). Corresponding RNA-seq data are presented for the same tissues.

Product Details

Tested Applications

Dilution

Immunocytochemistry (ICC)

1-4 µg/mL

Immunofluorescence (IF)

1-4 µg/mL

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

Product Specifications

Species Reactivity

Human

Host / Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human INHA

Conjugate

Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Product Specific Information

Immunogen sequence: QEAEEGLFRY MFRPSQHTRS RQVTSAQLWF HTGLDRQGTA ASNSSEPLLG LLALSPGGPV AVPMSLGHAP PHWAVLHLAT

Target Information

The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.