Invitrogen

INPP5A Polyclonal Antibody

Advanced Verification

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.

View all (8) INPP5A antibodies

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Datasheet

Protocols

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Tech Support

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INPP5A Antibody in Immunohistochemistry (IHC) — Immunohistochemical staining of INPP5A in human endometrium and liver tissues using INPP5A Polyclonal Antibody (Product # PA5-52921). Corresponding INPP5A RNA-seq data are presented for the same tissues.

INPP5A Antibody in Western Blot (WB) — Western blot analysis of INPP5A in control (vector only transfected HEK293T lysate) and INPP5A over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells). Samples were probed using a INPP5A Polyclonal Antibody (Product # PA5-52921).

INPP5A Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of INPP5A demonstrates antibody specificity. Immunohistochemical analysis of INPP5A using anti-INPP5A Polyclonal Antibody (Product # PA5-52921), shows significant staining of INPP5A in human endometrium and shows minimal or weak staining in human liver tissues. The relative expression levels of INPP5A within each tissue is shown using RNA-Seq. {RE}

Product Details

PA5-52921

Applications	Tested Dilution	Publications
Western Blot (WB)	0.04-0.4 µg/mL	-
Immunohistochemistry (IHC)	1:200-1:500	-

Product Specifications
Species Reactivity	Human
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Recombinant protein corresponding to Human INPP5A View antigen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.10 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.2, with 40% glycerol
Contains	0.02% sodium azide
Storage conditions	Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID	AB_2642733

Product Specific Information

Immunogen sequence: EVVKLIFRES DNDRKVMLQL EKKLFDYFNQ EVFRDNNGTA LLEFDKELSV FKDRLYELDI SFPPSYPYSE DARQGEQYMN TRCPAWCDRI LMSPSAKELV LRSESEEKVV TYDHIGPNVC MGDHKPVFL

Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.

Target Information

The protein encoded by this gene is a membrane-associated type I inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 43 kDa inositol polyphosphate 5-phophatase; 43 kDa inositol polyphosphate 5-phosphatase; 5PTase; CTCL tumor antigen HD-CL-02; DKFZp434A1721; Inositol polyphosphate-5-phosphatase A; inositol polyphosphate-5-phosphatase, 40kD; inositol polyphosphate-5-phosphatase, 40kDa; inositol trisphosphate-5-phosphatase, 40kD; InsP3 5-phosphatase; MGC116947; MGC116949; Type I inositol 1,4,5-trisphosphate 5-phosphatase; type I inositol-1,4,5-trisphosphate 5-phophatase; type I inositol-1,4,5-trisphosphate 5-phosphatase

Gene Aliases: 5PTASE; INPP5A

UniProt ID: (Human) Q14642

Entrez Gene ID: (Human) 3632

Molecular Function: phosphatase