FIGURE: 1 / 3
Recommended positive controls: HeLa, mouse brain.
Predicted reactivity: Mouse (91%), Rat (89%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
SAC2 is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase and contains a Sac domain. The activity of this protein is specific for phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Alternatively spliced transcript variants have been observed, but most of them are not thought to be protein-coding.
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Protein Aliases: EC 22.214.171.124; hSAC2; Inositol polyphosphate 5-phosphatase F; OCRL 1; Phosphatidylinositide phosphatase SAC2; Sac domain-containing inositol phosphatase 2; Sac domain-containing phosphoinositide 4-phosphatase 2; sac domain-containing phosphoinositide 5-phosphatase 2
Gene Aliases: hSAC2; INPP5F; KIAA0966; MSTP007; MSTP047; MSTPO47; SAC2
UniProt ID: (Human) Q9Y2H2
Entrez Gene ID: (Human) 22876
Molecular Function: phosphatase