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Product Details
PA5-21562
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 593 and 904 (Q9Y2H2) of INPP5F
Conjugate
Form
Liquid
Concentration
0.79 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_11152261
Product Specific Information
Recommended positive controls: HeLa, mouse brain.
Predicted reactivity: Mouse (91%), Rat (89%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
SAC2 is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase and contains a Sac domain. The activity of this protein is specific for phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Alternatively spliced transcript variants have been observed, but most of them are not thought to be protein-coding.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EC 3.1.3.36; hSAC2; Inositol polyphosphate 5-phosphatase F; OCRL 1; Phosphatidylinositide phosphatase SAC2; Sac domain-containing inositol phosphatase 2; Sac domain-containing phosphoinositide 4-phosphatase 2; sac domain-containing phosphoinositide 5-phosphatase 2
Gene Aliases: hSAC2; INPP5F; KIAA0966; MSTP007; MSTP047; MSTPO47; SAC2
UniProt ID: (Human) B3KRF1
Entrez Gene ID: (Human) 22876
protein binding
inositol monophosphate 1-phosphatase activity
phosphatidylinositol phosphate 5-phosphatase activity
phosphatidylinositol phosphate 4-phosphatase activity
protein homodimerization activity
inositol monophosphate 3-phosphatase activity
inositol monophosphate 4-phosphatase activity
phosphatase
positive regulation of receptor recycling
phosphatidylinositol biosynthetic process
cardiac muscle hypertrophy in response to stress
phosphatidylinositol catabolic process
negative regulation of tyrosine phosphorylation of Stat3 protein
phosphatidylinositol dephosphorylation
phosphatidylinositol-mediated signaling
negative regulation of axon regeneration
regulation of protein kinase B signaling
clathrin-mediated endocytosis
regulation of cell motility
regulation of endocytic recycling
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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