Search
Bethyl Laboratories
INPPL1/SHIP2 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
IHC-00567
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residues 100 and 150 of human inositol polyphosphate phosphatase-like 1.
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Rabbit, Monkey, Gorilla, Chimpanzee, Northern white-cheeked gibbon, Naked mole rat and Chinese hamster
Target Information
The protein encoded by this gene is an SH2-containing 5'-inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodeling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: 51C protein; Inositol polyphosphate phosphatase-like protein 1; INPPL-1; NS1; Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2; Protein 51C; PTP2C; SH-PTP2; SH2 domain-containing inositol 5'-phosphatase 2; SH2 domain-containing inositol phosphatase 2; SH2 domain-containing inositol-5'-phosphatase 2; SHP-2
Gene Aliases: INPPL1; OPSMD; SHIP2
UniProt ID: (Human) O15357
Entrez Gene ID: (Human) 3636
establishment of mitotic spindle orientation
endochondral ossification
immune system process
glucose metabolic process
lipid metabolic process
phosphatidylinositol biosynthetic process
endocytosis
apoptotic process
actin filament organization
cell adhesion
negative regulation of cell proliferation
post-embryonic development
gene expression
negative regulation of gene expression
response to insulin
regulation of protein localization
protein kinase B signaling
negative regulation of insulin-like growth factor receptor signaling pathway
phosphatidylinositol dephosphorylation
regulation of immune response
ERK1 and ERK2 cascade
ruffle assembly
regulation of actin filament organization
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support