The antibody can recognize isoforms 1, 2, 4, and 5 of INSC.
In Drosophila, neuroblasts divide asymmetrically into another neuroblast at the apical side and a smaller ganglion mother cell on the basal side. Cell polarization is precisely regulated by 2 apically localized multiprotein signaling complexes that are tethered by Inscuteable, which regulates their apical localization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: INSC; inscuteable spindle orientation adaptor protein; Minsc; Protein inscuteable homolog
Gene Aliases: 3830422K02Rik; C730020D23; INSC; RGD1311379