Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 1
Positive test controls include: Mouse brain.
Immunogen sequence: VTEFSPKLRQ VMLNEMLLLD IHTHEAGTGQ AGERPPSDLI SRVRGYLEMR LPDIPLRQVI AEECVAFMLN WRENEYLTLQ VPAFLLQSNP YVKLGQLLAA TCKELPGPKE SRRTAKDLWE VVVQICSVSS QHKRGNDGRV SLIKQRESTL GIMYRSELLS FIKKLREPLV LTIILSLFVK LHNVREDIVN DITAEHISIW P
This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ20530; Int8; Integrator complex subunit 8; MGC131633; Protein kaonashi-1
Gene Aliases: 2810013E07Rik; AV063769; C8orf52; D130008D20Rik; INT8; INTS8
UniProt ID: (Human) Q75QN2, (Mouse) Q80V86
Entrez Gene ID: (Human) 55656, (Mouse) 72656
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support