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Proteintech
INVS Polyclonal Antibody
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Product Details
10585-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
INVS Fusion Protein Ag0934 (1-101 aa encoded by BC006370)
Conjugate
Form
Liquid
Concentration
0.27 mg/mL
Amount
40.5 µg
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody is a rabbit polyclonal antibody raised against part of N-terminus of human INVS. The calculated molecular weight of INVS is 80 kDa, but the modified INVS protein is about 100-110 kDa.
Immunogen sequence: MNKSENLLF AGSSLASQVH AAAVNGDKGA LQRLIVGNSA LKDKEDQFGR TPLMYCVLAD RLDCADALLK AGADVNKTDH SQRTALHLAA QKALRTISTG RI (1-101 aa encoded by BC006370)
Target Information
This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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