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IP3 R3 Polyclonal Antibody
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Product Details
OST00430W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from aa region 1800-1850 of human IP3 receptor isoform 3 conjugated to blue carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: IP3 R3.
Target Information
This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: inositol 1,4,5-triphosphate receptor, type 3; inositol 1,4,5-trisphosphate receptor, type 3; Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3; insP3R3; IP3 receptor; IP3 receptor isoform 3; IP3R-3; Type 3 inositol 1,4,5-trisphosphate receptor; Type 3 InsP3 receptor
Gene Aliases: IP3R; IP3R3; ITPR3
UniProt ID: (Human) Q14573
Entrez Gene ID: (Human) 3710
inositol hexakisphosphate binding
inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
calcium ion binding
protein binding
calcium-release channel activity
phosphatidylinositol binding
inositol 1,3,4,5 tetrakisphosphate binding
inositol 1,4,5 trisphosphate binding
ligand-gated ion channel
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
memory
platelet activation
inositol phosphate-mediated signaling
regulation of insulin secretion
sensory perception of bitter taste
sensory perception of sweet taste
sensory perception of umami taste
release of sequestered calcium ion into cytosol
protein homooligomerization
protein heterooligomerization
response to calcium ion
long-term synaptic potentiation
calcium ion transport into cytosol
cellular response to cAMP
regulation of cardiac conduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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