Keep as concentrated solution.
Positive Control: mouse brain, rat brain.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
4; 5-trisphosphate receptor 1 antibody; D6Pas2 antibody; ENSMUSG00000072853 antibody; Gm10429 antibody; inositol 1; inositol 1,4,5-triphosphate receptor 1; inositol 1,4,5-triphosphate receptor, type 1; Inositol 1,4,5-trisphosphate receptor type 1; Inositol 1,4,5-trisphosphate-binding protein P400; InsP3R antibody; InsP3R type I; insP3R1; InsP>3
D6Pas2; ENSMUSG00000072853; Gm10429; I145TR; InsP3R; InsP3R1; Ip3r; IP3R1; Itpr-1; Itpr1; opt; P400; Pcd6; Pcp-1; Pcp1
Gene Aliases: D6Pas2; ENSMUSG00000072853; Gm10429; I145TR; InsP3R; InsP3R1; Ip3r; IP3R1; Itpr-1; Itpr1; opt; P400; Pcd6; Pcp-1; Pcp1