Immunogen sequence: MCVCQTMEVG QYGKNASRAG DRGVLLEPFI HQVGGHSSMM RYDDHTVCKP LISREQRFYE SLPPEMKEFT PEYKGVVSVC FEGDSDGYIN LVAYPYVESE TVEQDDTTER EQPRRKHSRR SLHRSGSGSD HKEEKASLSL ETSESSQEAK SPKVELHSHS EVPFQMLDGN SGLSSEKISH NPWSLRCHKQ QLSRMRSESK DRKLYKFLLL ENVVHHFKYP; Positive Samples: HeLa, 293T, HepG2, Mouse brain, Rat brain, Rat testis; Cellular Location: Cytoplasm, Nucleus
This gene encodes a member of the inositol phosphokinase family. The encoded protein may be responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternatively spliced transcript variants have been described.
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Protein Aliases: ATP:1D-myo-inositol-hexakisphosphate phosphotransferase; Inositol hexakisphosphate kinase 1; inositol hexakisphosphate kinase 6; Inositol hexaphosphate kinase 1; InsP6 kinase 1; Pi uptake stimulator
Gene Aliases: 1200016D08Rik; AU022776; IHPK1; InsP6; InsP6k1; IP6K1; Itpk6; KIAA0263; PiUS