PA5-28681 targets IP6K2 in IF and WB applications and shows reactivity with Human samples.
The PA5-28681 immunogen is recombinant fragment corresponding to a region within amino acids 171 and 426 of Human IP6K2.
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This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 and affect the growth suppressive and apoptotic activities of interferon-beta in some ovarian cancers. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Protein Aliases: ATP:1D-myo-inositol-hexakisphosphate phosphotransferase; IHPK2; Inositol hexakisphosphate kinase 2; inositol hexaphosphate kinase 2; InsP6 kinase 2; P(i)-uptake stimulator; pi uptake stimulator; PIUS
Gene Aliases: IHPK2; IP6K2; PIUS; TCCCIA00113
UniProt ID: (Human) Q9UHH9
Entrez Gene ID: (Human) 51447