|Western Blot (WB)||1-3 µg/ml|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide corresponding to the N terminus amino acids NKPITPSTYVRC.|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. [supplied by RefSeq]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: interleukin-1; interleukin-1 receptor associated kinase 4; Interleukin-1 receptor-associated kinase 4; IRAK-4; IRAK-4 mutated form 1; IRAK4; NY-REN-64; REN64; Renal carcinoma antigen NY-REN-64
Gene Aliases: 8430405M07Rik; 9330209D03Rik; IPD1; IRAK-4; IRAK4; NY-REN-64; REN64
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