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Proteintech
IREB2 Polyclonal Antibody
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Product Details
29976-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
IREB2 fusion protein Ag32233
Conjugate
Form
Liquid
Concentration
0.6 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: VRNCDGFLMK KEDVMNILDW KTKQSNVEVP FFPARVLLQD FTGIPAMVDF AAMREAVKTL GGDPEKVHPA CPTDLTVDHS LQIDFSKCAI QNAPNPGGGD LQKAGKLSPL KVQPKKLPCR GQTTCRGSCD SGELGRNSGT FSSQIENTPI LCPFHLQPVP EPETVLKNQE VEFGRNRERL QFFKWSSRVF KNVAVIPPGT GMAHQI
Target Information
Iron regulatory protein 2 (IRP2) is a central post-transcriptional regulator of cellular and systemic iron metabolism. It is a cytosolic RNA-binding protein that binds to stem-loop structures. IRP2 is regulated by iron-mediated proteolysis. Hypoxia is important for normal tissue physiology as well as being a component of several pathophysiological conditions, including heart and cerebrovascular diseases and tumor growth. Because iron and oxygen are closely related, IRP2 also plays a role during hypoxia (low oxygen).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ23381; IRE-BP 2; Iron regulatory protein 2; iron-responsive element binding protein 2; Iron-responsive element-binding protein 2; IRP2
Gene Aliases: ACO3; D9Ertd85e; IREB2; IRP2; IRP2AD
UniProt ID: (Human) P48200, (Mouse) Q811J3
Entrez Gene ID: (Human) 3658, (Mouse) 64602
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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