This antibody has 94% sequence homology with human, primate and rat.
Suggested positive control: 3T3 whole cell lysate.
Iron regulatory protein 2 (IRP2) is a central post-transcriptional regulator of cellular and systemic iron metabolism. It is a cytosolic RNA-binding protein that binds to stem-loop structures. IRP2 is regulated by iron-mediated proteolysis. Hypoxia is important for normal tissue physiology as well as being a component of several pathophysiological conditions, including heart and cerebrovascular diseases and tumor growth. Because iron and oxygen are closely related, IRP2 also plays a role during hypoxia (low oxygen).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ23381; IRE-BP 2; Iron regulatory protein 2; Iron-responsive element-binding protein 2; IRP2
Gene Aliases: D9Ertd85e; Ireb2; Irp2
UniProt ID: (Mouse) Q811J3
Entrez Gene ID: (Mouse) 64602