Immunogen sequence: LGSMPGLMPP GLLAAAVSGL GSRGLTLAPG LSPARPLFGS DFEKEKQQRN ADCLAELNEA MRGRAEEWHG RPKAVREQL
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.
IRF2BP1 acts as a transcriptional repressor. IRF2BP1 also acts as a transcriptional corepressor in a IRF2-dependent manner. This repression is not mediated at least in part by histone deacetylase activities.
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Protein Aliases: DKFZP434M154; Interferon regulatory factor 2-binding protein 1; IRF-2-binding protein 1; Probable E3 ubiquitin-protein ligase IRF2BP1; Probable RING-type E3 ubiquitin transferase IRF2BP1
Gene Aliases: IRF2BP1
UniProt ID: (Human) Q8IU81
Entrez Gene ID: (Human) 26145
Molecular Function: zinc finger transcription factor