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Product Details
PA5-28138
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to a region within amino acids 405 and 467 of Human IRF6
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2545614
Product Specific Information
Recommended positive controls: IRF6 tansfected 293T cell.
Predicted reactivity: Rhesus Monkey (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Interferon regulatory factor 6; IRF-6
Gene Aliases: AI876454; E230028I05Rik; IRF6; LPS; mirf6; OFC6; PIT; PPS; PPS1; VWS; VWS1
UniProt ID: (Human) G0ZTL0, (Mouse) P97431
Entrez Gene ID: (Human) 3664, (Rat) 364081, (Mouse) 54139
transcription, DNA-templated
cell cycle arrest
negative regulation of cell proliferation
keratinocyte differentiation
keratinocyte proliferation
positive regulation of transcription, DNA-templated
cell development
interferon-gamma-mediated signaling pathway
type I interferon signaling pathway
mammary gland epithelial cell differentiation
biological_process
skin development
regulation of transcription, DNA-templated
cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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