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Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
0.1-1 µg/mL | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
2-10 µg/mL | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
A synthetic peptide corresponding to the epitope ASSPA without phosphorylation site Ser 731 of human IRS-2 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.5 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS with proprietary stabilizer |
Contains |
0.01% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Positive control: Human kidney
Cellular location: Cytoplasm.
This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 4PS; Insulin receptor substrate 2; IRS-2; tyrosine kinase substrate
Gene Aliases: 4PS; IRS-2; IRS2
UniProt ID: (Human) Q9Y4H2, (Mouse) P81122
Entrez Gene ID: (Human) 8660, (Rat) 29376, (Mouse) 384783
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