|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 882 and 1178 of Human IRS1|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:5000-1:20,000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Miscellaneous PubMed (MISC)||See 1 publications below|
PA5-29667 targets IRS1 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-29667 immunogen is recombinant fragment corresponding to a region within amino acids 882 and 1178 of Human IRS1.
This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Autophagy Correlates with the Therapeutic Responsiveness of Malignant Pleural Mesothelioma in 3D Models.
PA5-29667 was used in immunohistochemistry - paraffin section to assess the activity of a novel dual PI3K/mTOR inhibitor on mesothelioma
|Barbone D,Follo C,Echeverry N,Gerbaudo VH,Klabatsa A,Bueno R,Felley-Bosco E,Broaddus VC||PloS one (10:null)||2015|