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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • ISCU Antibodies

          Proteintech

          ISCU Polyclonal Antibody, CoraLite® Plus 488

          View all (15) ISCU antibodies

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          Cite ISCU Polyclonal Antibody, CoraLite® Plus 488

          • Antibody Testing Data (1)
          ISCU Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          ISCU Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          ISCU Antibody (CL488-14812) in ICC/IF

          Immunofluorescent analysis of (4% PFA) fixed MCF-7 cells using CoraLite® Plus 488 ISCU antibody (CL488-14812) at dilution of 1:200, CL594-Phalloidin (red). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          ISCU Antibody in Immunocytochemistry (ICC/IF)

          Product Details

          CL488-14812

          Applications
          Tested Dilution
          Publications

          Immunocytochemistry (ICC/IF)

          1:50-1:500
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          ISCU fusion protein Ag6562

          Conjugate

          CoraLite® Plus 488 CoraLite® Plus 488 CoraLite® Plus 488

          Excitation/Emission Max

          493/522 nm

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 0.5% BSA, 50% glycerol

          Contains

          0.05% ProClin 300

          Storage conditions

          -20°C, store in dark

          Shipping conditions

          Wet ice

          Product Specific Information

          Immunogen sequence: MAAAGAFRL RRAASALLLR SPRLPARELS APARLYHKKV VDHYENPRNV GSLDKTSKNV GTGLVGAPAC GDVMKLQIQV DEKGKIVDAR FKTFGCGSAI ASSSLATEWV KGKTVEEALT IKNTDIAKEL CLPPVKLHCS MLAEDAIKAA LADYKLKQEP KKGEAEKK

          Target Information

          Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Iron-sulfur cluster assembly enzyme ISCU; iron-sulfur cluster assembly enzyme ISCU, mitochondrial; iron-sulfur cluster scaffold homolog; IscU iron-sulfur cluster scaffold homolog; ISCU2; NifU-like N-terminal domain containing; NifU-like N-terminal domain-containing protein; NifU-like protein

          View more View less

          Gene Aliases: 2310020H20Rik; AA407971; HML; hnifU; ISCU; ISU2; NIFU; NIFUN; RGD1309562

          View more View less

          UniProt ID: (Human) Q9H1K1, (Mouse) Q9D7P6

          View more View less

          Entrez Gene ID: (Human) 23479, (Mouse) 66383, (Rat) 288740

          View more View less

          Function(s)
          iron ion binding protein binding ferrous iron binding protein complex scaffold iron-sulfur transferase activity 2 iron, 2 sulfur cluster binding 4 iron, 4 sulfur cluster binding metal ion binding iron-sulfur cluster binding chaperone
          Process(es)
          cellular iron ion homeostasis nitrogen fixation iron-sulfur cluster assembly small molecule metabolic process [2Fe-2S] cluster assembly protein maturation by iron-sulfur cluster transfer
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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