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          • Primary Antibodies ›
          • ISCU Antibodies

          Invitrogen

          ISCU Monoclonal Antibody (OTI4F5)

          1 Reference
          View all (13) ISCU antibodies

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          Cite ISCU Monoclonal Antibody (OTI4F5)

          Additional Information:
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          • Antibody Testing Data (4)
          ISCU Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          ISCU Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 4

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          ISCU Antibody (MA5-26595) in IHC (P)

          Immunohistochemistry was performed on paraffin-embedded human lymphoma tissue. To expose target proteins, 10mM citric buffer, pH6.0, 120°C for 3min was used. Following antigen retrieval, tissues were probed with a ISCU monoclonal antibody (Product # MA5-26595). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          ISCU Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ISCU Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ISCU Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          ISCU Antibody in Western Blot (WB)
          ISCU Monoclonal Antibody (OTI4F5)

          Product Details

          MA5-26595

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:2,000
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:150
          -
          Product Specifications

          Species Reactivity

          Human

          Published species

          Human

          Host/Isotype

          Mouse / IgG1

          Class

          Monoclonal

          Type

          Antibody

          Clone

          OTI4F5

          Immunogen

          Full length human recombinant protein of ISCU produced in E.coli
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Affinity Chromatography

          Storage buffer

          PBS, pH 7.3, with 1% BSA, 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2723295

          Target Information

          Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Iron-sulfur cluster assembly enzyme ISCU; iron-sulfur cluster assembly enzyme ISCU, mitochondrial; iron-sulfur cluster scaffold protein; IscU iron-sulfur cluster scaffold homolog; NifU-like N-terminal domain-containing protein; NifU-like protein; unnamed protein product

          View more View less

          Gene Aliases: 2310020H20Rik; HML; hnifU; ISCU; ISU2; NIFU; NIFUN

          View more View less

          UniProt ID: (Human) Q9H1K1

          View more View less

          Entrez Gene ID: (Human) 23479

          View more View less

          Function(s)
          iron ion binding protein binding ferrous iron binding zinc ion binding protein homodimerization activity metal ion binding iron-sulfur cluster binding 2 iron, 2 sulfur cluster binding binding, bridging iron-sulfur cluster chaperone activity
          Process(es)
          cellular iron ion homeostasis iron-sulfur cluster assembly [2Fe-2S] cluster assembly [4Fe-4S] cluster assembly positive regulation of mitochondrial electron transport, NADH to ubiquinone negative regulation of iron ion import across plasma membrane
          It has to be done as per old AB suggested Products section.

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          Close

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