Interferon-induced antiviral exoribonuclease that acts on single-stranded RNA and also has minor activity towards single-stranded DNA. Exhibits antiviral activity against RNA viruses including hepatitis C virus (HCV), hepatitis A virus (HAV) and yellow fever virus (YFV) in an exonuclease-dependent manner. May also play additional roles in the maturation of snRNAs and rRNAs, and in ribosome biogenesis. [UniProt]
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Protein Aliases: Estrogen-regulated transcript 45 protein; interferon stimulated exonuclease; interferon stimulated exonuclease 20; interferon stimulated exonuclease gene 20kDa; interferon stimulated gene 20kDa; Interferon-stimulated gene 20 kDa protein; interferon-stimulated protein; Promyelocytic leukemia nuclear body-associated protein ISG20; Protein DnaQL
Gene Aliases: 1600023I01Rik; 2010107M23Rik; 20kDa; CD25; DnaQL; HEM45; ISG20