Immunogen sequence: TSTDRLLWRE AKLDHCRRVS LRVLSERLLH KSIQNSLLGH SSVEDARATM
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Predicted homology: Cow: 79%; Dog: 85%; Guinea Pig: 85%; Horse: 86%; Human: 100%; Pig: 100%; Rabbit: 86%; Rat: 92%
Interferon-induced antiviral exoribonuclease that acts on single-stranded RNA and also has minor activity towards single-stranded DNA. Exhibits antiviral activity against RNA viruses including hepatitis C virus (HCV), hepatitis A virus (HAV) and yellow fever virus (YFV) in an exonuclease-dependent manner. May also play additional roles in the maturation of snRNAs and rRNAs, and in ribosome biogenesis. [UniProt]
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Protein Aliases: Estrogen-regulated transcript 45 protein; interferon stimulated exonuclease gene 20kDa; Interferon-stimulated gene 20 kDa protein; Promyelocytic leukemia nuclear body-associated protein ISG20
Gene Aliases: CD25; HEM45; ISG20
UniProt ID: (Human) Q96AZ6
Entrez Gene ID: (Human) 3669