Immunogen sequence: AQALENHTEV QFQKECGPDN KCESNLQMRA AFVSEQQQKL SRLQYSRDVR KLLLSINVTN TRTSERSGED AHEALLTLVV PPALLLSSVR PPGACQANET IFCELGNPFK RNQRMELLIA FEVIGV
The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis. [provided by RefSeq, Oct 2015]
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Protein Aliases: alpha 3 subunit of VLA-3 receptor; antigen CD49C; antigen identified by monoclonal antibody J143; CD49 antigen-like family member C; CD49c; FRP-2; Galactoprotein B3; GAP-B3; GAPB3; integrin alpha 3; Integrin alpha-3; Integrin alpha-3 heavy chain; Integrin alpha-3 light chain; integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor); MSK18; testicular tissue protein Li 96; testicular tissue protein Li 98; VCA-2; very late activation protein 3 receptor, alpha-3 subunit; VLA-3 subunit alpha; VLA3a
Gene Aliases: CD49C; FRP-2; GAP-B3; GAPB3; ILNEB; ITGA3; MSK18; VCA-2; VL3A; VLA3a
UniProt ID: (Human) P26006