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Invitrogen
ITGA7 Polyclonal Antibody
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FIGURE: 1 / 1
ITGA7 Antibody (PA5-89699) in WB
Western blot analysis of ITGA7 in extracts of U-87MG cells. Samples were incubated with ITGA7 Polyclonal antibody (Product # PA5-89699) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-89699
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 880-1020 of human ITGA7 (NP_0021972)
Conjugate
Form
Liquid
Concentration
1.82 mg/mL
Amount
182 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: QVELEGGQGP GQKGLCSPRP NILHLDVDSR DRRRRELEPP EQQEPGERQE PSMSWWPVSS AEKKKNITLD CARGTANCVV FSCPLYSFDR AAVLHVWGRL WNSTFLEEYS AVKSLEVIVR ANITVKSSIK NLMLRDASTV I; Positive Samples: U-87MG; Cellular Location: Membrane, Single-pass type I membrane protein
Target Information
Integrin alpha-7 is a protein that in humans is encoded by the ITGA7 gene. This gene is mapped to 12q13.2. The protein encoded by this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis. This protein functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in this gene are associated with congenital myopathy.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: integrin alpha 7 chain; Integrin alpha-7; transmembrane protein; unnamed protein product
Gene Aliases: ITGA7; UNQ406/PRO768
UniProt ID: (Human) Q13683
Entrez Gene ID: (Human) 3679
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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