ITLN1 has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. ITLN1 increases AKT phosphorylation in the absence and presence of insulin. ITLN1 may play a role in the defense system against microorganisms. ITLN1 may specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. ITLN1 may be involved in iron metabolism.
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Protein Aliases: calcium-dependent galactosyl-specific lectin; Endothelial lectin HL 1; Endothelial lectin HL-1; Galactofuranose binding lectin; Galactofuranose-binding lectin; hIntL; HL 1; HL1; Intelectin 1; intelectin 1 (galactofuranose binding); intelectin 1 (galactofuranose binding)-like; intelectin 2; intelectin 5; intelectin a; Intelectin-1; Intelectin-1a; Intestinal lactoferrin receptor; INTL; ITLN; ITLN 1; ITLN-1; ITLN1; LFR; Omentin
Gene Aliases: hIntL; HL-1; HL1; INTL; ITLN; ITLN1; Itln1a; Itln2; Itln5; Itlna; LFR; omentin; UNQ640/PRO1270