The synthetic peptide sequence is 19-59aa, TDEANTYFKEWTCSSSPSLPRSCKEIKDECPSAFDGLYFLR
Add 0.2 mL of distilled water, will yield a concentration of 500 µg/mL.
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed.
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Protein Aliases: Endothelial lectin HL-1; Galactofuranose-binding lectin; intelectin 1 (galactofuranose binding); Intelectin-1; Intestinal lactoferrin receptor; ITLN-1; Omentin
Gene Aliases: hIntL; HL-1; HL1; INTL; ITLN; ITLN1; LFR; omentin; UNQ640/PRO1270
UniProt ID: (Human) Q8WWA0
Entrez Gene ID: (Human) 55600