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Invitrogen
ITPKA Polyclonal Antibody
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FIGURE: 1 / 3
ITPKA Antibody (PA5-75226) in WB
Western blot analysis of ITPKA in Lane 1: A549 whole cell lysate (40 µg), Lane 2: MCF-7 whole cell lysate (40 µg), Lane 3: HEK293T whole cell lysate (40 µg), Lane 4: AML-12 whole cell lysate (40 µg), Lane 5: H9C2 whole cell lysate (40 µg). Samples were incubated with ITPKA polyclonal antibody (Product # PA5-75226) at a dilution of 1:500.
Product Details
PA5-75226
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids 400-450 of Human ITPKA.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EC 2.7.1.127; inositol 1,4,5-triphosphate 3-kinase; Inositol 1,4,5-trisphosphate 3-kinase A; inositol 145-triphosphate 3-kinase; Inositol-trisphosphate 3-kinase A; insP 3-kinase A; IP3 3 kinase A; IP3 3-kinase A; IP3-kinase A; IP3K A
Gene Aliases: IP3-3KA; IP3KA; ITPKA
UniProt ID: (Human) P23677, (Mouse) Q8R071, (Rat) P17105
Entrez Gene ID: (Human) 3706, (Mouse) 228550, (Rat) 81677
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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