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Proteintech
IVNS1ABP Polyclonal Antibody
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Product Details
14741-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
IVNS1ABP Fusion Protein Ag6412 (301-633 aa encoded by BC067739)
Conjugate
Form
Liquid
Concentration
0.19 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: TYLCLAVLD GIFCVIFLHG RNSPQSSPTS TPKLSKSLSF EMQQDELIEK PMSPMQYARS GLGTAEMNGK LIAAGGYNRE ECLRTVECYN PHTDHWSFLA PMRTPRARFQ MAVLMGQLYV VGGSNGHSDD LSCGEMYDSN IDDWIPVPEL RTNRCNAGVC ALNGKLYIVG GSDPYGQKGL KNCDVFDPVT KLWTSCAPLN IRRHQSAVCE LGGYLYIIGG AESWNCLNTV ERYNPENNTW TLIAPMNVAR RGAGVAVLNG KLFVCGGFDG SHAISCVEMY DPTRNEWKMM GNMTSPRSNA GIATVGNTIY AVGGFDGNEF LNTVEVYNLE SNEW (301-633 aa encoded by B C067739)
Target Information
IVNS1ABP is a protein coding gene involved in many cell functions, including pre-mRNA splicing, the aryl hydrocarbon receptor (AHR) pathway, F-actin organization and protein ubiquitination. Plays a role in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription. In addition, functions as a negative regulator of BCR(KLHL20) E3 ubiquitin ligase complex to prevent ubiquitin-mediated proteolysis of PML and DAPK1, two tumor suppressors. Inhibits pre-mRNA splicing (in vitro).; (Microbial infection) involved in the alternative splicing of influenza A virus M1 mRNA through interaction with HNRNPK, thereby facilitating the generation of viral M2 protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: aryl hydrocarbon receptor-associated 3; Aryl hydrocarbon receptor-associated protein 3; Influenza virus NS1A-binding protein; Influenza virus NS1A-binding protein homolog; kelch family protein Nd1; Kelch family protein Nd1-L; kelch-like family member 39; Kelch-like protein 39; NCX downstream gene 1; ND1-L2; Nd1-S; NS1-binding protein; NS1-binding protein homolog; NS1-BP
Gene Aliases: 1190004M08Rik; 1700126I16Rik; AA960440; ARA3; FLARA3; HSPC068; IVNS1ABP; KIAA0850; KLHL39; mKIAA0850; ND1; Nd1-L; Nd1-S; Nd1L; Nd1S; NS-1; NS1; NS1-BP; NS1BP
UniProt ID: (Human) Q9Y6Y0, (Mouse) Q920Q8
Entrez Gene ID: (Human) 10625, (Mouse) 117198, (Rat) 289089
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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