Fabgennix

Inhibin alpha Polyclonal Antibody, FITC

Product Details

INBN-1-FITC

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:1,000	-
Immunohistochemistry (IHC)	1:50-1:250	-
Immunocytochemistry (ICC/IF)	1:50-1:250	-
ELISA (ELISA)	1:10,000	-
Immunoprecipitation (IP)	1:50-1:250	-
Immunomicroscopy (IM)	1:50-1:200	-

Product Specifications
Species Reactivity	Human, Mouse, Non-human primate, Rat
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	N-epitope synthetic peptide taken within amino acid region 1-50 on Inhibin alpha gene. View immunogen
Conjugate	FITC
Excitation/Emission Profile	View spectra
Form	Liquid
Concentration	0.5-1.5 mg/mL
Purification	Affinity chromatography
Storage buffer	proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains	0.02% sodium azide
Storage conditions	-20° C, store in dark

Target Information

The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.