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          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • CD51/CD61 Antibodies

          Bioss

          Integrin Alpha V + Beta 3 Polyclonal Antibody

          View all (12) CD51/CD61 antibodies

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          Cite Integrin Alpha V + Beta 3 Polyclonal Antibody

          • Antibody Testing Data (3)
          Integrin Alpha V + Beta 3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          Integrin Alpha V + Beta 3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          Integrin Alpha V + Beta 3 Antibody (BS-1310R) in IHC (P)

          Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti Integrin Alpha V + Beta 3 (CD51+CD61)Polyclonal Antibody, Unconjugated (bs-1310R) at 1:200 followed by conjugation to the secondary antibody and DAB staining. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Integrin Alpha V + Beta 3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Integrin Alpha V + Beta 3 Antibody in Flow Cytometry (Flow)
          Integrin Alpha V + Beta 3 Antibody in Flow Cytometry (Flow)

          Product Details

          BS-1310R

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:300-1:1,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200
          -

          Immunohistochemistry (Frozen) (IHC (F))

          1:100-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:200
          -

          Flow Cytometry (Flow)

          0.2 µg
          -

          ELISA (ELISA)

          1:500-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          KLH conjugated synthetic peptide derived from human Integrin Alpha V + Beta 3.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein A

          Storage buffer

          0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

          Contains

          0.02% ProClin 300

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          CD51 and CD61 molecules (alpha V and beta 3 integrins) form a complex. This complex binds vitronection at the RGD sequence and can also bind fibrinogen, von Willebrand factor, thrombospondin, fibronectin, osteopontin and collagen. Reacts with osteoclasts, placenta, melanoma cell lines and weakly with platelets.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: alpha v integrin; antigen CD61; antigen identified by monoclonal antibody L230; CD51; CD61; Dnmt3l-ps1 pseudogene; GPIIIa; integrin alpha V; integrin alpha-5 beta-3; Integrin alpha-V; integrin alphaVbeta3; integrin beta 3; integrin beta 3 (Cd61); Integrin beta-3; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); platelet gpIIIa; Platelet membrane glycoprotein IIIa; Vitronectin receptor; vitronectin receptor alpha polypeptide (VNRA); Vitronectin receptor subunit alpha

          View more View less

          Gene Aliases: 1110004F14Rik; 2610028E01Rik; BDPLT16; BDPLT2; CD51; CD61; D430040G12Rik; GP3A; GPIIIa; GT; INGRB3; ITGAV; ITGB3; MSK8; VNRA; VTNR

          View more View less

          UniProt ID: (Human) P06756, (Human) P05106, (Mouse) P43406, (Rat) Q8R2H2, (Mouse) O54890

          View more View less

          Entrez Gene ID: (Human) 3685, (Human) 3690, (Rat) 296456, (Mouse) 16410, (Rat) 29302, (Mouse) 16416

          View more View less

          Function(s)
          virus receptor activity opsonin binding fibronectin binding protease binding protein kinase C binding voltage-gated calcium channel activity protein binding coreceptor activity fibroblast growth factor binding C-X3-C chemokine binding insulin-like growth factor I binding neuregulin binding metal ion binding transforming growth factor beta binding extracellular matrix binding extracellular matrix protein binding protein disulfide isomerase activity platelet-derived growth factor receptor binding enzyme binding identical protein binding vascular endothelial growth factor receptor 2 binding cell adhesion molecule binding receptor binding peptide binding protein heterodimerization activity integrin binding fibrinogen binding receptor activity integrin
          Process(es)
          angiogenesis antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent cell adhesion cell-matrix adhesion integrin-mediated signaling pathway positive regulation of cell proliferation negative regulation of macrophage derived foam cell differentiation negative regulation of lipid storage cell growth cell migration extracellular matrix organization positive regulation of cell migration cell-substrate adhesion negative regulation of lipid transport positive regulation of osteoblast proliferation heterotypic cell-cell adhesion substrate adhesion-dependent cell spreading endodermal cell differentiation apolipoprotein A-I-mediated signaling pathway apoptotic cell clearance negative regulation of low-density lipoprotein particle receptor biosynthetic process positive regulation of cell adhesion viral entry into host cell vascular endothelial growth factor receptor signaling pathway negative regulation of lipoprotein metabolic process regulation of phagocytosis leukocyte migration negative chemotaxis entry of symbiont into host cell by promotion of host phagocytosis ERK1 and ERK2 cascade calcium ion transmembrane transport extrinsic apoptotic signaling pathway in absence of ligand regulation of apoptotic cell clearance negative regulation of entry of bacterium into host cell negative regulation of extrinsic apoptotic signaling pathway positive regulation of protein phosphorylation positive regulation of endothelial cell proliferation platelet degranulation cell-substrate junction assembly blood coagulation positive regulation of endothelial cell migration smooth muscle cell migration platelet activation positive regulation of vascular endothelial growth factor receptor signaling pathway activation of protein kinase activity tube development wound healing regulation of bone resorption mesodermal cell differentiation positive regulation of peptidyl-tyrosine phosphorylation angiogenesis involved in wound healing platelet aggregation blood vessel development vasculogenesis cellular calcium ion homeostasis positive regulation of cytosolic calcium ion concentration positive regulation of MAPK cascade inflammatory response multicellular organism development fertilization cell differentiation detection of molecule of bacterial origin regulation of ion transmembrane transport gonad morphogenesis T cell activation endothelial cell migration focal adhesion assembly release of sequestered calcium ion into cytosol trophoblast giant cell differentiation response to nitric oxide positive regulation of leukocyte migration protein folding embryo implantation regulation of G-protein coupled receptor protein signaling pathway response to radiation positive regulation of fibroblast migration response to activity positive regulation of smooth muscle cell migration regulation of cell migration positive regulation of cell adhesion mediated by integrin cellular response to drug response to platelet-derived growth factor positive regulation of angiogenesis positive regulation of bone resorption positive regulation of smooth muscle cell proliferation regulation of release of sequestered calcium ion into cytosol negative regulation of cell death positive regulation of ERK1 and ERK2 cascade cellular response to mechanical stimulus positive regulation of glomerular mesangial cell proliferation positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway cellular response to insulin-like growth factor stimulus positive regulation of osteoclast differentiation cell projection morphogenesis
          It has to be done as per old AB suggested Products section.
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