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          • Primary Antibodies ›
          • CD51/CD61 Antibodies

          Bioss

          Integrin Alpha V + Beta 3 Polyclonal Antibody

          View all (14) CD51/CD61 antibodies

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          Cite Integrin Alpha V + Beta 3 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (3)
          Integrin Alpha V + Beta 3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          Integrin Alpha V + Beta 3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          Integrin Alpha V + Beta 3 Antibody (BS-1310R) in IHC (P)

          Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti Integrin Alpha V + Beta 3 (CD51+CD61)Polyclonal Antibody, Unconjugated (bs-1310R) at 1:200 followed by conjugation to the secondary antibody and DAB staining. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          View Product

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          Integrin Alpha V + Beta 3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Integrin Alpha V + Beta 3 Antibody in Flow Cytometry (Flow)
          Integrin Alpha V + Beta 3 Antibody in Flow Cytometry (Flow)

          Product Details

          BS-1310R

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:300-1:1,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200
          -

          Immunohistochemistry (Frozen) (IHC (F))

          1:100-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:200
          -

          Flow Cytometry (Flow)

          0.2 µg
          -

          ELISA (ELISA)

          1:500-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          KLH conjugated synthetic peptide derived from human Integrin Alpha V + Beta 3.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Protein A

          Storage buffer

          0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

          Contains

          0.02% ProClin 300

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          CD51 and CD61 molecules (alpha V and beta 3 integrins) form a complex. This complex binds vitronection at the RGD sequence and can also bind fibrinogen, von Willebrand factor, thrombospondin, fibronectin, osteopontin and collagen. Reacts with osteoclasts, placenta, melanoma cell lines and weakly with platelets.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: alpha v integrin; antigen CD61; antigen identified by monoclonal antibody L230; CD51; CD61; Dnmt3l-ps1 pseudogene; glycoprotein IIIa precursor; GPIIIa; integrin alpha-5 beta-3; Integrin alpha-V; integrin alphaVbeta3; integrin beta 3; integrin beta 3 (Cd61); integrin beta chain, beta 3; Integrin beta-3; integrin beta-3 subunit; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); plate glycoprotein IIIa (GPIIIa); platelet gpIIIa; Platelet membrane glycoprotein IIIa; unnamed protein product; vitronectin alpha subunit precursor; Vitronectin receptor; vitronectin receptor alpha polypeptide (VNRA); Vitronectin receptor subunit alpha

          View more View less

          Gene Aliases: 1110004F14Rik; 2610028E01Rik; BDPLT16; BDPLT2; BDPLT24; CD51; CD61; D430040G12Rik; GP3A; GPIIIa; GT; GT2; INGRB3; ITGAV; ITGB3; MSK8; VNRA; VTNR

          View more View less

          UniProt ID: (Human) P06756, (Human) P05106, (Mouse) P43406, (Rat) Q8R2H2, (Mouse) O54890

          View more View less

          Entrez Gene ID: (Human) 3685, (Human) 3690, (Rat) 296456, (Mouse) 16410, (Rat) 29302, (Mouse) 16416

          View more View less

          Function(s)
          virus receptor activity opsonin binding fibronectin binding protease binding protein kinase C binding receptor binding integrin binding protein binding coreceptor activity fibroblast growth factor binding C-X3-C chemokine binding insulin-like growth factor I binding signaling receptor activity neuregulin binding metal ion binding transforming growth factor beta binding extracellular matrix binding extracellular matrix protein binding protein disulfide isomerase activity platelet-derived growth factor receptor binding enzyme binding identical protein binding vascular endothelial growth factor receptor 2 binding cell adhesion molecule binding fibrinogen binding voltage-gated calcium channel activity peptide binding protein heterodimerization activity receptor activity integrin
          Process(es)
          angiogenesis blood vessel development vasculogenesis formation of primary germ layer cell adhesion cell-matrix adhesion positive regulation of cytosolic calcium ion concentration integrin-mediated signaling pathway positive regulation of cell proliferation tissue development negative regulation of macrophage derived foam cell differentiation negative regulation of lipid storage negative regulation of low-density lipoprotein particle clearance cell migration positive regulation of cell migration cell-substrate adhesion negative regulation of lipid transport cell adhesion mediated by integrin positive regulation of osteoblast proliferation heterotypic cell-cell adhesion substrate adhesion-dependent cell spreading wound healing, spreading of epidermal cells endodermal cell differentiation apolipoprotein A-I-mediated signaling pathway apoptotic cell clearance positive regulation of cell adhesion viral entry into host cell negative regulation of lipoprotein metabolic process regulation of phagocytosis negative chemotaxis positive regulation of small GTPase mediated signal transduction ERK1 and ERK2 cascade calcium ion transmembrane transport transforming growth factor beta production entry into host cell by a symbiont-containing vacuole extrinsic apoptotic signaling pathway in absence of ligand cell-cell adhesion positive regulation of intracellular signal transduction negative regulation of entry of bacterium into host cell negative regulation of extrinsic apoptotic signaling pathway positive regulation of endothelial cell proliferation positive regulation of cell-matrix adhesion positive regulation of leukocyte migration cell-substrate junction assembly embryo implantation blood coagulation regulation of G-protein coupled receptor protein signaling pathway positive regulation of endothelial cell migration positive regulation of gene expression positive regulation of fibroblast migration response to activity smooth muscle cell migration positive regulation of smooth muscle cell migration platelet activation positive regulation of vascular endothelial growth factor receptor signaling pathway regulation of protein localization regulation of actin cytoskeleton organization positive regulation of cell adhesion mediated by integrin tube development response to platelet-derived growth factor cellular response to platelet-derived growth factor stimulus wound healing regulation of bone resorption positive regulation of angiogenesis positive regulation of bone resorption platelet-derived growth factor receptor signaling pathway positive regulation of fibroblast proliferation mesodermal cell differentiation positive regulation of smooth muscle cell proliferation regulation of developmental process regulation of transport regulation of release of sequestered calcium ion into cytosol regulation of serotonin uptake angiogenesis involved in wound healing regulation of biological quality positive regulation of ERK1 and ERK2 cascade platelet aggregation cellular response to mechanical stimulus cellular response to xenobiotic stimulus positive regulation of glomerular mesangial cell proliferation blood coagulation, fibrin clot formation maintenance of postsynaptic specialization structure regulation of postsynaptic neurotransmitter receptor internalization regulation of postsynaptic neurotransmitter receptor diffusion trapping positive regulation of substrate adhesion-dependent cell spreading positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway positive regulation of vascular endothelial growth factor signaling pathway regulation of trophoblast cell migration regulation of extracellular matrix organization cellular response to insulin-like growth factor stimulus negative regulation of endothelial cell apoptotic process positive regulation of T cell migration cellular calcium ion homeostasis cell growth positive regulation of MAPK cascade negative regulation of low-density lipoprotein particle receptor biosynthetic process regulation of apoptotic cell clearance inflammatory response multicellular organism development fertilization cell differentiation detection of molecule of bacterial origin regulation of ion transmembrane transport gonad morphogenesis T cell activation endothelial cell migration focal adhesion assembly release of sequestered calcium ion into cytosol trophoblast giant cell differentiation response to nitric oxide protein folding response to radiation regulation of cell migration activation of protein kinase activity cellular response to drug positive regulation of peptidyl-tyrosine phosphorylation negative regulation of cell death positive regulation of osteoclast differentiation cell projection morphogenesis
          It has to be done as per old AB suggested Products section.

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          Host server : magellan-search-blue-67655d8755-b2k9d:80/100.66.79.173:80.
          git-commit: dddaa802cd395f65bf1581942d0e97a089c38f41
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.46.0-Offline