Bioss

Integrin Alpha V + Beta 6 Polyclonal Antibody

View all (2) ITGAV/ITGB6 antibodies

Questions & Answers

Questions & Answers

Product Image Gallery

Integrin Alpha V + Beta 6 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Formalin-fixed and paraffin embedded human gastric carcinoma labeled with Anti-Integrin Alpha V + Beta 6 Polyclonal Antibody, Unconjugated (bs-5791R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.

Integrin Alpha V + Beta 6 Antibody in Western Blot (WB) — Mouse kidney lysates probed with Integrin Alpha V + Beta 6 Polyclonal Antibody, Unconjugated (bs-5791R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37°C.

Integrin Alpha V + Beta 6 Antibody in Western Blot (WB) — Siha cell lysates probed with Integrin Alpha V + Beta 6 Polyclonal Antibody, Unconjugated (bs-5791R) at 1:300 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37°C.

Integrin Alpha V + Beta 6 Antibody in Flow Cytometry (Flow) — Hela cells probed with Integrin Alpha V + Beta 6 Antibody, Unconjugated (bs-5791R) at 1:100 for 30 minutes followed by incubation with a conjugated secondary (PE Conjugated) (green) for 30 minutes compared to control cells (blue), secondary only (light blue) and isotype control (orange).

Product Details

Applications

Tested Dilution

Publications

Western Blot (WB)

1:300

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200

-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

Flow Cytometry (Flow)

1:100

-

ELISA (ELISA)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human Integrin Alpha V + Beta 6.

Conjugate

Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS with 1% BSA, 50% glycerol

Contains

0.09% sodium azide

Storage conditions

-20°C

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: alpha v integrin; antigen identified by monoclonal antibody L230; CD51; Dnmt3l-ps1 pseudogene; integrin alpha V; Integrin alpha-V; Integrin alpha-V heavy chain; Integrin alpha-V light chain; integrin alphaVbeta3; integrin beta 6; Integrin beta-6; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); integrin, beta 6; Vitronectin receptor; vitronectin receptor alpha polypeptide (VNRA); Vitronectin receptor subunit alpha

Gene Aliases: 1110004F14Rik; 2210409C20Rik; 2610028E01Rik; 4831415H04Rik; AI1H; CD51; D430040G12Rik; ITGAV; ITGB6; MSK8; VNRA; VTNR

UniProt ID: (Human) P06756, (Human) P18564, (Mouse) P43406, (Rat) Q6AYF4, (Mouse) Q9Z0T9

Entrez Gene ID: (Human) 3685, (Human) 3694, (Rat) 296456, (Mouse) 16410, (Rat) 311061, (Mouse) 16420

Molecular Function: integrin

angiogenesis antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent cell adhesion cell-matrix adhesion integrin-mediated signaling pathway positive regulation of cell proliferation negative regulation of macrophage derived foam cell differentiation negative regulation of lipid storage cell growth cell migration extracellular matrix organization positive regulation of cell migration cell-substrate adhesion negative regulation of lipid transport positive regulation of osteoblast proliferation heterotypic cell-cell adhesion substrate adhesion-dependent cell spreading endodermal cell differentiation apolipoprotein A-I-mediated signaling pathway apoptotic cell clearance negative regulation of low-density lipoprotein particle receptor biosynthetic process positive regulation of cell adhesion viral entry into host cell vascular endothelial growth factor receptor signaling pathway negative regulation of lipoprotein metabolic process regulation of phagocytosis leukocyte migration negative chemotaxis entry of symbiont into host cell by promotion of host phagocytosis ERK1 and ERK2 cascade calcium ion transmembrane transport extrinsic apoptotic signaling pathway in absence of ligand regulation of apoptotic cell clearance negative regulation of entry of bacterium into host cell negative regulation of extrinsic apoptotic signaling pathway inflammatory response blood vessel development vasculogenesis cellular calcium ion homeostasis positive regulation of cytosolic calcium ion concentration positive regulation of MAPK cascade multicellular organism development fertilization cell differentiation detection of molecule of bacterial origin regulation of ion transmembrane transport gonad morphogenesis T cell activation endothelial cell migration regulation of bone resorption focal adhesion assembly release of sequestered calcium ion into cytosol trophoblast giant cell differentiation response to nitric oxide biological_process

Process(es)

virus receptor activity opsonin binding fibronectin binding protease binding protein kinase C binding voltage-gated calcium channel activity protein binding coreceptor activity fibroblast growth factor binding C-X3-C chemokine binding insulin-like growth factor I binding neuregulin binding metal ion binding transforming growth factor beta binding extracellular matrix binding extracellular matrix protein binding integrin binding receptor binding peptide binding protein heterodimerization activity molecular_function receptor activity