PA5-30582 targets Involucrin in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-30582 immunogen is synthetic peptide corresponding to a region within amino acids 50 and 142 of Human Involucrin.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin.
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Protein Aliases: Involucrin
Gene Aliases: IVL
UniProt ID: (Human) P07476
Entrez Gene ID: (Human) 3713