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Product Details
PA5-60756
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human JAKMIP1
Conjugate
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
AB_2642842
Product Specific Information
Immunogen sequence: LVEKNKRMNK KNEDLLQSIQ RMEEKIKNLT RENVEMKEKL SAQASLKRHT SLNDLSLTRD EQEIEFLRLQ VLEQQHVIDD LSL
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 96%.
Target Information
JAKMIP1, also known as Marlin-1, is a highly-conserved vertebrate-specific microtubule-associated protein that plays a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements. JAKMIP1 is expressed predominantly in neuronal and lymphoid cells and colocalizes with microtubules. Multiple isoforms of JAKMIP1 are known to exist: isoforms 1 and 5 are also expressed in liver, lung and skeletal muscle, while isoforms 2-4 are specifically expressed in brain and retina. JAKMIP1 participates in polarized secretion in lymphocytes and it has been suggested to be a novel effector memory gene restraining T cell-mediated cytotoxicity. Dysregulation of JAKMIP1 gene expression is associated with genetic conditions linked to autism in humans.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ31564; GABA-B receptor-binding protein; Jak and microtubule interacting protein 1; Janus kinase and microtubule-interacting protein 1; Marlin-1; Multiple alpha-helices and RNA-linker protein 1; multiple coiled-coil GABABR1-binding protein
Gene Aliases: GABABRBP; JAKMIP1; JAMIP1; MARLIN1
UniProt ID: (Human) Q96N16
Entrez Gene ID: (Human) 152789
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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