Immunogen sequence: THLPGKRPAR GSLPEQPCTK KARADHGLIP DVKLEKTVPR LHRPSLQHFR EQFLVPGRPV ILKGVADHWP CMQKWSLEYI QEIAGCRTVP VEVGSRYTDE EWSQTLMTVN EFISKYIVNE PRDVGYLAQH QLFDQIPELK QDISIPDYCS LGDGEEEEIT INAWFGPQGT ISPLHQDPQQ NFLVQVMGRK YIRLYSPQES GALYPHDTHL LHNTSQVDVE NPDLEKFPKF AKAPFLSCIL SPGEILFIPV KYWHYVRALD LSFSVSFWWS; Positive Samples: LO2, Mouse eye, Mouse liver; Cellular Location: Nucleus
This gene likely encodes a histone lysine demethylase. Studies of a similar protein in mouse indicate a potential role for this protein as a tumor suppressor. Alternatively spliced transcript variants have been described.
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Protein Aliases: Bifunctional peptidase and arginyl-hydroxylase JMJD5; JmjC domain-containing protein 5; Jumonji C domain-containing protein 5; jumonji domain containing 5; jumonji domain-containing protein 5; L-arginine (3R)-hydroxylase KDM8; lysine (K)-specific demethylase 8; Lysine-specific demethylase 8
Gene Aliases: 3110005O21Rik; JMJD5; KDM8; RGD1304823