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Proteintech
JMJD6 Polyclonal Antibody
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Product Details
16476-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
JMJD6 Fusion Protein Ag9590 (1-403 aa encoded by BC066654)
Conjugate
Form
Liquid
Concentration
0.37 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MNHKSKKRI REAKRSARPE LKDSLDWTRH NYYESFSLSP AAVADNVERA DALQLSVEEF VERYERPYKP VVLLNAQEGW SAQEKWTLER LKRKYRNQKF KCGEDNDGYS VKMKMKYYIE YMESTRDDSP LYIFDSSYGE HPKRRKLLED YKVPKFFTDD LFQYAGEKRR PPYRWFVMGP PRSGTGIHID PLGTSAWNAL VQGHKRWCLF PTSTPRELIK VTRDEGGNQQ DEAITWFNVI YPRTQLPTWP PEFKPLEILQ KPGETVFVPG GWWHVVLNLD TTIAITQNFA SSTNFPVVWH KTVRGRPKLS RKWYRILKQE HPELAVLADS VDLQESTGIA SDSSSDSSSS SSSSSSDSDS ECESGSEGDG TVHRRKKRRT CSMVGNGDTT SQDDCVSKER SSSR (1-403 aa encoded by BC066654)
Target Information
This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells; however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: apoptotic cell clearance receptor PtdSerR; Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6; Histone arginine demethylase JMJD6; JmjC domain-containing protein 6; jumonji domain containing 6; Jumonji domain-containing protein 6; Lysyl-hydroxylase JMJD6; Peptide-lysine 5-dioxygenase JMJD6; Phosphatidylserine receptor; Protein PTDSR
Gene Aliases: 5730436I23Rik; D11Ertd195e; JMJD6; KIAA0585; mKIAA0585; PSR; PtdSerR; PTDSR; PTDSR1
UniProt ID: (Human) Q6NYC1, (Mouse) Q9ERI5, (Rat) Q6AYK2
Entrez Gene ID: (Human) 23210, (Mouse) 107817, (Rat) 360665
RNA binding
single-stranded RNA binding
receptor activity
iron ion binding
protein binding
histone demethylase activity
histone demethylase activity (H3-R2 specific)
histone demethylase activity (H4-R3 specific)
identical protein binding
protein homodimerization activity
peptidyl-lysine 5-dioxygenase activity
sulfonate dioxygenase activity
oxidoreductase activity
2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity
procollagen-proline dioxygenase activity
hypophosphite dioxygenase activity
DNA-N1-methyladenine dioxygenase activity
metal ion binding
dioxygenase activity
C-19 gibberellin 2-beta-dioxygenase activity
C-20 gibberellin 2-beta-dioxygenase activity
molecular_function
protein modifying enzyme
kidney development
sprouting angiogenesis
transcription, DNA-templated
regulation of transcription, DNA-templated
mRNA processing
cell surface receptor signaling pathway
heart development
RNA splicing
peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine
lung development
T cell differentiation in thymus
macrophage activation
recognition of apoptotic cell
regulation of mRNA splicing, via spliceosome
erythrocyte development
oxidation-reduction process
retina development in camera-type eye
histone H3-R2 demethylation
histone H4-R3 demethylation
blood vessel development
multicellular organism development
chromatin modification
cell differentiation
apoptotic cell clearance
biological_process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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